Amphetamines

Amphetamines be part of a class of drugs called stimulants that affect the central nervous system. It is also known as 1-methyl-2-phenethylamine, 1-phenyl-2-aminopropane, and Benzedrine. It is made up of a 50/50 mixture of the l and d isomers. The l isomer affects the body, and the d isomer affects the brain. It boils at 200ºC and is soluble in alcohol and ether, slightly soluble in water. It was postmortem created in Germany in 1887. In the 1930s and 40s amphetamine was occasion in the treatment of asthma, depression, obesity, and narcolepsy. Amphetamines chemical structure is very resembling to the neurotransmitter Adrenaline. chemical substance structure of Amphetamine, C H CH CH(NH ) CH Method of Preparation thither are many ways of creating amphetamines. unity way is to unsay two mols, for example, 270 grams, of racemic amphetamine base to play off with hotshot mol (150 grams) of d-tartaric hot, forming a dl-amphetamine d-tartrate, or a unbiased salt. The indifferent salt obtained is dissolved by the addition of nearly 1 litre, of ethanol, and heating to boiling point. The solution then must(prenominal) be cooled to get on temperature with occasional stirring to effect crystallisation. The crystals are filtered out and go out be found to contain laevo enantiomorph, which is the left wing of a pair of crystals that are a mirror regard of apiece other.

It is then recrystallised and the predominance of the l-enantiomorph is found to be change order of magnitude and the process is repeated until no further change is accomplished and a concentration of 8 grams per 100 cc of sedimentary solution is obtained. Finally the product ob tained is l-amphetamine d-tartrate. d-amphet! amine may be line up from this by the addition of tartaric irate for the formation of acid tartrates and separation of d-amphetamine d-bitartrate by crystallisation. Properties and Chemical Reactions of Amphetamines Amphetamines vary... If you want to get a full essay, order it on our website: OrderEssay.net

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